| 產(chǎn)品編號(hào) | bs-0346R-HRP |
| 英文名稱 | Rabbit Anti-Rat IgM antibody |
| 中文名稱 | 辣根過(guò)氧化物酶標(biāo)記的兔抗大鼠IgM |
| 別 名 | Rabbit Anti-Rat IgM (HRP); Immunoglobulin M; |
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Specific References (3) | bs-0346R-HRP has been referenced in 3 publications.
[IF=5.116] Chunyu Jiang. et al. Upregulating CXCR7 accelerates endothelial progenitor cell-mediated endothelial repair by activating Akt/Keap-1/Nrf2 signaling in diabetes mellitus. Stem Cell Res Ther. 2021 Dec;12(1):1-15 WB ; Rat.
[IF=2.784] Guo X et al.RP105 ameliorates hypoxia?reoxygenation injury in cardiac microvascular endothelial cells by suppressing TLR4?MAPKs?NF-κB signaling.Int J Mol Med. 2018 Jul;42(1):505-513. WB ; Rat.
[IF=0.46] Su, Yuqing, et al. "Mixed PEGylated surfactant modifying system decrease the accelerated blood clearance phenomenon of nanoemulsions in rats."Asian Journal of Pharmaceutical Sciences (2016). ELISA ; Rat.
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| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-10000,IHC-P=1:100-500,IHC-F=1:100-1000,ELISA=1:1000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Liquid |
| 濃 度 | 2.0 mg/ml |
| 免 疫 原 | Native Rat IgM |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol. |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
