| 產品編號 | bs-7577R |
| 英文名稱 | Rabbit Anti-SLC25A6 antibody |
| 中文名稱 | 線粒體載體腺嘌呤核苷酸轉運蛋白6抗體 |
| 別 名 | Adenine nucleotide translocator 3; ADP ATP carrier protein 3; ADP ATP carrier protein isoform T2; ADP ATP carrier protein liver; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 3; ANT3; ANT3Y; MGC17525; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6; Solute carrier family 25 member 6; ADT3_HUMAN. |
| 研究領域 | 細胞生物 信號轉導 轉錄調節因子 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Zebrafish,Chicken,Dog) |
| 產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細胞定位 | 細胞漿 細胞膜 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC25A6: 56-150/298 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
SLC25A6 (solute carrier family 25, member A6) participates in the exchange of ADP and ATP across the mitochondrial inner membrane. It may be involved in the formation of the permeability transition pore complex (PTPC), a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. Opening of the PTPC causes massive swelling of mitochondria, rupture of the outer membrane and release of intermembrane components that induce apoptosis. Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Subunit: Found in a complex with ARL2, ARL2BP and SLC25A6. Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Similarity: Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats. SWISS: P12236 Gene ID: 293 Database links: Entrez Gene: 293 Human Omim: 300151 Human Omim: 403000 Human SwissProt: P12236 Human Unigene: 350927 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
