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Rabbit Anti-GLUT10  antibody (bs-6325R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-6325R
英文名稱 Rabbit Anti-GLUT10  antibody
中文名稱 葡萄糖轉運蛋白10抗體
別    名 facilitated glucose transporter member 10; Glucose Transporter GLUT10; AA450473; Glucose transporter type 10; glut 10; GLUT10; GLUT-10; GTR10_HUMAN; MGC126706; SLC2A10; Solute carrier family 2; Solute carrier family 2, facilitated glucose transporter member 10.  
研究領域 心血管  細胞生物  信號轉導  糖尿病  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Cow,Dog)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 67kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GLUT10: 288-335/541 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.

Function:
Facilitative glucose transporter.

Subcellular Location:
Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.

Tissue Specificity:
Widely expressed; highest levels in liver and pancreas.

Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

SWISS:
O95528

Gene ID:
81031

Database links:
UniProtKB/Swiss-Prot: O95528.2

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