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Rabbit Anti-ELOVL2  antibody (bs-7053R)  
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產品編號 bs-7053R
英文名稱 Rabbit Anti-ELOVL2  antibody
中文名稱 長鏈脂肪酸延長酶ELOVL2抗體
別    名 3 keto acyl CoA synthase ELOVL2; 3-keto acyl-CoA synthase Elovl2; Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2; Elongation of very long chain fatty acids protein 2; ELOV2_HUMAN; ELOVL fatty acid elongase 2; Elovl2; FLJ20334; OTTHUMP00000016029; SSC2; ELOVL2.  
Specific References  (2)     |     bs-7053R has been referenced in 2 publications.
[IF=6.166] Dawoon Jeong. et al. ELOVL2: a novel tumor suppressor attenuating tamoxifen resistance in breast cancer. Am J Cancer Res. 2021; 11(6): 2568–2589  WB ;  Human.  
[IF=3.231] Jiamei Liu. et al. Composition of Fatty Acids and Localization of SREBP1 and ELOVL2 Genes in Cauda Epididymides of Hu Sheep with Different Fertility. ANIMALS. 2022 Jan;12(23):3302  IHC ;  Sheep.  
研究領域 心血管  細胞生物  信號轉導  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Pig,Cow)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELOVL2: 201-296/296 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.

Function:
Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Liver and testis.

Similarity:
Belongs to the ELO family.

SWISS:
Q9NXB9

Gene ID:
54898

Database links:

Entrez Gene: 54898 Human

Entrez Gene: 54326 Mouse

Entrez Gene: 498728 Rat

Omim: 611814 Human

SwissProt: Q9NXB9 Human

SwissProt: Q9JLJ4 Mouse

Unigene: 656436 Human

Unigene: 2567 Mouse



產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ELOVL2) Polyclonal Antibody, Unconjugated (bs-7053R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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