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FSTL1 Rabbit pAb (bs-6050R)  
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產(chǎn)品編號 bs-6050R
英文名稱 FSTL1 Rabbit pAb
中文名稱 卵泡抑素相關(guān)蛋白1抗體
別    名 FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN.  
研究領(lǐng)域 心血管  細胞生物  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FSTL1/FRP: 201-308/308 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Function:
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin.

Subunit:
Interacts with SCN10A.

Subcellular Location:
Secreted.

Tissue Specificity:
Overexpressed in synovial tissues from rheumatoid arthritis.

Similarity:
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain.

Gene ID:
11167

Database links:

Entrez Gene: 534482 Cow

Entrez Gene: 11167 Human

Entrez Gene: 14314 Mouse

Entrez Gene: 79210 Rat

Omim: 605547 Human

SwissProt: Q58D84 Cow

SwissProt: Q12841 Human

SwissProt: Q62356 Mouse

SwissProt: Q62632 Rat

Unigene: 269512 Human

Unigene: 182434 Mouse

Unigene: 95652 Rat



產(chǎn)品圖片
Sample: Lane 1: Human U-2 OS cell lysates Lane 2: Human HeLa cell lysates Lane 3: Human HUVEC cell lysates Lane 4: Human A431 cell lysates Primary: Anti-FSTL1 (bs-6050R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kDa Observed band size: 47 kDa
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