| 產品編號 | bs-1446R |
| 英文名稱 | Rabbit Anti-TRAP1/HSP75 antibody |
| 中文名稱 | 熱休克蛋白75抗體 |
| 別 名 | TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; TRAP1_HUMAN. |
| 研究領域 | 腫瘤 細胞生物 免疫學 信號轉導 細胞凋亡 轉錄調節因子 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Chicken,Horse) |
| 產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 74kDa |
| 細胞定位 | 細胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSP75: 501-650/704 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function: Chaperone that expresses an ATPase activity. Subunit: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1. Subcellular Location: Mitochondrion. Tissue Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta. Similarity: Belongs to the heat shock protein 90 family. SWISS: Q12931 Gene ID: 10131 Database links: Entrez Gene: 10131 Human Entrez Gene: 68015 Mouse Entrez Gene: 416666 Chicken Omim: 606219 Human SwissProt: Q12931 Human SwissProt: Q9CQN1 Mouse Unigene: 30345 Human Unigene: 123366 Mouse Unigene: 144695 Rat 信號傳導（Signaling Intermediates） HSP75/TRAP-1與TNF受體發生相互作用,可產生促進TNF的信號轉導。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
